Mouse Amphiregulin/AREG protein (Recombinant) (N-hFc) (STJP020371)
SPECIFICATIONS
HostHEK293 cells
ConjugationUnconjugated
ImmunogenRecombinant Mouse Amphiregulin/AREG Protein is produced by HEK293 cells expression system. The target protein is expressed with sequence (Val100-Ala248) of Mouse Amphiregulin/AREG (Accession #NP_033834.1) fused with hFc tag at the N-terminus.
General Information
| Short Description | Recombinant-Mouse Amphiregulin/AREG-N-hFc protein was developed in hek293 cells using the region Val100-Ala248. For use in research applications. |
| Host | HEK293 cells |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Conjugation | Unconjugated |
| Formulation | Lyophilised from a 0.22 Mu m filtered solution of PBS, pH 7.4. Contact us for customized product form or formulation. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Determination Method | < 1 EU/Mu g of the protein by LAL method. |
Target Information
| Gene Symbol | Areg |
| Gene ID | 11839 |
| Uniprot ID | AREG_MOUSE |
| Immunogen | Recombinant Mouse Amphiregulin/AREG Protein is produced by HEK293 cells expression system. The target protein is expressed with sequence (Val100-Ala248) of Mouse Amphiregulin/AREG (Accession #NP_033834.1) fused with hFc tag at the N-terminus. |
| Immunogen Region | Val100-Ala248 |
| Immunogen Sequence | VIKPKKNKTEGEKSTEKPKR KKKGGKNGKGRRNKKKKNPC TAKFQNFCIHGECRYIENLE VVTCNCHQDYFGERCGEKSM KTHSEDDKDLSKIAVVAVTI FVSAIILAAIGIGIVITVHL WKRYFREYEGETEERRRLRQ ENGTVHAIA |
Additional Info
| Function | Ligand of the EGF receptor/EGFR. Autocrine growth factor as well as a mitogen for a broad range of target cells including astrocytes, Schwann cells and fibroblasts. |
| Protein Name | AmphiregulinArSchwannoma-Derived Growth FactorSdgf |
| Database Links | Reactome: R-MMU-1257604Reactome: -MMU-177929Reactome: -MMU-179812Reactome: -MMU-180292Reactome: -MMU-180336Reactome: -MMU-182971Reactome: -MMU-204005Reactome: -MMU-212718Reactome: -MMU-5673001Reactome: -MMU-5694530Reactome: -MMU-6811558Reactome: -MMU-8856825Reactome: -MMU-8856828Reactome: -MMU-9009391 |
| Cellular Localisation | MembraneSingle-Pass Membrane Protein |
| Alternative Protein Names | Amphiregulin proteinAr proteinSchwannoma-Derived Growth Factor proteinSdgf proteinAreg proteinSdgf protein |
Information sourced from Uniprot.org