Mouse ADCYAP1 (Adenylate Cyclase Activating Polypeptide 1, Pituitary) Sandwich ELISA Kit Ready-To-Use Kit (STJE0013292)
SPECIFICATIONS
General Information
| Short Description | This ADCYAP1 Sandwich ELISA Kit, Ready-To-Use is an in-vitro enzyme-linked immunosorbent assay for the measurement of samples in mouse serum, plasma, tissue homogenates or other biological fluids.. |
| Applications | ELISA |
| Reactivity | Mouse |
| Sensitivity | 28pg/mL |
| Detection Limit | 78.1-5000pg/mL |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Storage Instruction | The whole kit may be stored at-20°C for up to 12 months from receipt. An unopened kit may be stored in the fridge at 2-8°C for up to 6 months. Once opened store individual kit contents according to components table provided with the kit. |
| Assay Time | 3 hrs |
Target Information
| Gene Symbol | Adcyap1 |
| Gene ID | 11516 |
| Uniprot ID | PACA_MOUSE |
| Immunogen Region | Ready-To-Use |
| Sample Type | serum, plasma, tissue homogenates or other biological fluids. |
Additional Info
| Tissue Specificity | |
| Post Translational Modifications | |
| Function | PACAP is a neuropeptide involved in diverse array of physiological processes through activating the PACAP subfamily of class B1 G protein-coupled receptors: VIP receptor 1 (VIPR1), VIP receptor 2 (VIPR2), and PACAP type I receptor (ADCYAP1R1). Exerts neuroprotective and general cytoprotective effects due to anti-apoptotic, anti-inflammatory, and antioxidant actions. Promotes neuron projection development through the RAPGEF2/Rap1/B-Raf/ERK pathway. In chromaffin cells, induces long-lasting increase of intracellular calcium concentrations and neuroendocrine secretion. Involved in the control of glucose homeostasis, induces insulin secretion by pancreatic beta cells. PACAP exists in two bioactive forms from proteolysis of the same precursor protein, PACAP27 and PACAP38, which differ by eleven amino acid residues in the C-terminus. |
| Protein Name | Pituitary Adenylate Cyclase-Activating PolypeptidePacap Cleaved Into - Pacap-Related PeptidePrp-48 - Pituitary Adenylate Cyclase-Activating Polypeptide 27Pacap-27Pacap27 - Pituitary Adenylate Cyclase-Activating Polypeptide 38Pacap-38Pacap38 |
| Database Links | Reactome: R-MMU-418555Reactome: -MMU-420092 |
| Cellular Localisation | Secreted |
| Alternative ELISA Names | Pituitary Adenylate Cyclase-Activating Polypeptide ELISA kitPacap Cleaved Into - Pacap-Related Peptide ELISA kitPrp-48 - Pituitary Adenylate Cyclase-Activating Polypeptide 27 ELISA kitPacap-27 ELISA kitPacap27 - Pituitary Adenylate Cyclase-Activating Polypeptide 38 ELISA kitPacap-38 ELISA kitPacap38 ELISA kitAdcyap1 ELISA kitPacap ELISA kit |
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Information sourced from Uniprot.org