Mouse ACTH (Adrenocorticotropic Hormone) Competitive ELISA Kit (STJE0006873)

SKU:
STJE0006873
£401.50 - £545.50
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Applications: ELISA
Reactivity: Mouse
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Sensitivity: 6.39pg/mL
Detection Limit: 15.6-1000pg/mL
Short Description : This ACTH Competitive ELISA Kit is an in-vitro enzyme-linked immunosorbent assay for the measurement of samples in mouse serum, plasma or other biological fluids.
Storage Instruction: Store the unopened kit in the fridge at 2-8°C for up to 6 months. Once opened store individual kit contents according to components table provided with the kit.
Assay Time: 2.5 hrs
Gene Symbol: Pomc
Gene ID: 18976
Uniprot ID: COLI_MOUSE
Sample Type: serum, plasma or other biological fluids.
Tissue Specificity ACTH and MSH are produced by the pituitary gland.
Post Translational Modifications Specific enzymatic cleavages at paired basic residues yield the different active peptides.
Function Corticotropin: Stimulates the adrenal glands to release cortisol. Melanocyte-stimulating hormone alpha: Anorexigenic peptide. Increases the pigmentation of skin by increasing melanin production in melanocytes. Melanocyte-stimulating hormone beta: Increases the pigmentation of skin by increasing melanin production in melanocytes. Beta-endorphin: Endogenous orexigenic opiate. Met-enkephalin: Endogenous opiate.
Protein Name Pro-Opiomelanocortin
Pomc
Corticotropin-Lipotropin Cleaved Into - Npp - Melanotropin Gamma
Gamma-Msh - Corticotropin
Adrenocorticotropic Hormone
Acth - Melanocyte-Stimulating Hormone Alpha
Alpha-Msh
Melanotropin Alpha - Corticotropin-Like Intermediary Peptide
Clip - Lipotropin Beta
Beta-Lph - Lipotropin Gamma
Gamma-Lph - Melanocyte-Stimulating Hormone Beta
Beta-Msh
Melanotropin Beta - Beta-Endorphin - Met-Enkephalin
Database Links Reactome: R-MMU-111885
Reactome: -MMU-193048
Reactome: -MMU-194002
Reactome: -MMU-202040
Reactome: -MMU-209952
Reactome: -MMU-211976
Reactome: -MMU-375276
Reactome: -MMU-418555
Reactome: -MMU-418594
Cellular Localisation Secreted
Melanocyte-Stimulating Hormone Alpha And Beta-Endorphin Are Stored In Separate Granules In Hypothalamic Pomc Neurons
Suggesting That Secretion May Be Under The Control Of Different Regulatory Mechanisms
Alternative ELISA Names Pro-Opiomelanocortin ELISA kit
Pomc ELISA kit
Corticotropin-Lipotropin Cleaved Into - Npp - Melanotropin Gamma ELISA kit
Gamma-Msh - Corticotropin ELISA kit
Adrenocorticotropic Hormone ELISA kit
Acth - Melanocyte-Stimulating Hormone Alpha ELISA kit
Alpha-Msh ELISA kit
Melanotropin Alpha - Corticotropin-Like Intermediary Peptide ELISA kit
Clip - Lipotropin Beta ELISA kit
Beta-Lph - Lipotropin Gamma ELISA kit
Gamma-Lph - Melanocyte-Stimulating Hormone Beta ELISA kit
Beta-Msh ELISA kit
Melanotropin Beta - Beta-Endorphin - Met-Enkephalin ELISA kit
Pomc ELISA kit
Pomc1 ELISA kit
output

Information sourced from Uniprot.org