| Tissue Specificity | |
| Post Translational Modifications | Glycosylated. |
| Function | ATP-dependent transporter of the ATP-binding cassette (ABC) family that actively extrudes physiological compounds, and xenobiotics from cells. Mediates ATP-dependent transport of glutathione conjugates such as leukotriene-c4 (LTC4) and N-ethylmaleimide S-glutathione (NEM-GS) (in vitro), and an anionic cyclopentapeptide endothelin antagonist, BQ-123. May contribute to regulate the transport of organic compounds in testes across the blood-testis-barrier. Mediates the release of nucleoside triphosphates, predominantly ATP, into the circulation, where it is rapidly converted into AMP and the mineralization inhibitor inorganic pyrophosphate (PPi) by the ecto-enzyme ectonucleotide pyrophosphatase phosphodiesterase 1 (ENPP1), therefore playing a role in PPi homeostasis. |
| Protein Name | Atp-Binding Cassette Sub-Family C Member 6Multidrug Resistance-Associated Protein 6 |
| Database Links | Reactome: R-MMU-382556 |
| Cellular Localisation | Basolateral Cell MembraneMulti-Pass Membrane ProteinBasal Cell Membrane |
| Alternative ELISA Names | Atp-Binding Cassette Sub-Family C Member 6 ELISA kitMultidrug Resistance-Associated Protein 6 ELISA kitAbcc6 ELISA kitMrp6 ELISA kit |
| output | |
Information sourced from Uniprot.org
