| Applications: |
WB |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
MINPP1 Positive Control for STJ501756 is synthetically produced from the sequence and is suitable for use in western blot applications. |
| Formulation: |
Provided as 100 uL ready-to-use, in SDS-PAGE sample buffer (Laemelli's buffer) containing Tris, pH 6.8, 1 % SDS, Glycerol and Bromophenolblue blue as tracking dye. The sample is reduced by adding 2% beta mercaptoethanol. The protein concentration is |
| Dilution Range: |
WB: 1:500 |
| Storage Instruction: |
Store at-20°C for long term storage. Avoid freeze-thaw cycles. |
| Gene Symbol: |
MINPP1 |
| Gene ID: |
9562 |
| Uniprot ID: |
MINP1_HUMAN |
| Specificity: |
This is positive control is recommended for use in combination with MINPP1 antibody STJ501756. |
| Function | Acts as a phosphoinositide 5- and phosphoinositide 6-phosphatase and regulates cellular levels of inositol pentakisphosphate (InsP5) and inositol hexakisphosphate (InsP6). Also acts as a 2,3-bisphosphoglycerate 3-phosphatase, by mediating the dephosphorylation of 2,3-bisphosphoglycerate (2,3-BPG) to produce phospho-D-glycerate without formation of 3-phosphoglycerate. May play a role in bone development (endochondral ossification). May play a role in the transition of chondrocytes from proliferation to hypertrophy. Through the regulation of intracellular inositol polyphosphates, may control intracellular cation homeostasis, including that of calcium and iron, hence affecting free cation availability required for neural cell signaling. |
| Peptide Name | Multiple Inositol Polyphosphate Phosphatase 12 -3-Bisphosphoglycerate 3-Phosphatase2 -3-Bpg PhosphataseInositol1 -3 -4 -5-Tetrakisphosphate 3-PhosphataseIns(1 -3 -4 -5p(4 3-Phosphatase |
| Database Links | Reactome: R-HSA-1855231 |
| Cellular Localisation | Endoplasmic Reticulum Lumen |
| Alternative Peptide Names | Multiple Inositol Polyphosphate Phosphatase 1 protein2 -3-Bisphosphoglycerate 3-Phosphatase protein2 -3-Bpg Phosphatase proteinInositol protein1 -3 -4 -5-Tetrakisphosphate 3-Phosphatase proteinIns(1 -3 -4 -5p(4 3-Phosphatase proteinMINPP1 proteinMIPP proteinUNQ900 proteinPRO1917 protein |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
