| Applications: | WB |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description : | MC4 Receptor Positive Control is synthetically produced from the sequence and is suitable for use in western blot applications. |
| Formulation: | Provided as 100 uL ready-to-use, in SDS-PAGE sample buffer (Laemelli's buffer) containing Tris, pH 6.8, 1 % SDS, Glycerol and Bromophenolblue blue as tracking dye. The sample is reduced by adding 2% beta mercaptoethanol. The protein concentration is |
| Dilution Range: | WB: 1:500 |
| Storage Instruction: | Store at-20°C for long term storage. Avoid freeze-thaw cycles. |
| Gene Symbol: | MC4R |
| Gene ID: | 4160 |
| Uniprot ID: | MC4R_HUMAN |
| Tissue Specificity | Brain, placental, and gut tissues. |
| Function | Receptor specific to the heptapeptide core common to adrenocorticotropic hormone and alpha-, beta-, and gamma-MSH. Plays a central role in energy homeostasis and somatic growth. This receptor is mediated by G proteins that stimulate adenylate cyclase (cAMP). |
| Peptide Name | Melanocortin Receptor 4 Mc4-R |
| Database Links | Reactome: R-HSA-375276 Reactome: R-HSA-418555 Reactome: R-HSA-9856649 |
| Cellular Localisation | Cell Membrane Multi-Pass Membrane Protein |
| Alternative Peptide Names | Melanocortin Receptor 4 protein Mc4-R protein MC4R protein |
Information sourced from Uniprot.org