Tissue Specificity | Expressed in neutrophils. |
Function | Acyltransferase which catalyzes the transfer of an acyl group from an acyl-CoA towards a lysophospholipid producing a phospholipid and participates in the reacylation step of the phospholipid remodeling pathway also known as the Lands cycle. Acts on lysophosphatidylserine (1-acyl-2-hydroxy-sn-glycero-3-phospho-L-serine or LPS) and lysophosphatidylethanolamine (1-acyl-sn-glycero-3-phosphoethanolamine or LPE), and to a lesser extend lysophosphatidylcholine. Prefers oleoyl-CoA as the acyl donor and 1-oleoyl-LPE as acceptor. May play a role in neurite outgrowth during neuronal differentiation. |
Peptide Name | Lysophospholipid Acyltransferase 1Lplat 11-Acylglycerophosphocholine O-Acyltransferase1-Acylglycerophosphoethanolamine O-Acyltransferase1-Acylglycerophosphoserine O-Acyltransferase Mboat1Lysophosphatidylserine AcyltransferaseLpsatLyso-Ps AcyltransferaseMembrane-Bound O-Acyltransferase Domain-Containing Protein 1O-Acyltransferase Domain-Containing Protein 1 |
Database Links | Reactome: R-HSA-1482801Reactome: R-HSA-1482839 |
Cellular Localisation | MembraneMulti-Pass Membrane Protein |
Alternative Peptide Names | Lysophospholipid Acyltransferase 1 proteinLplat 1 protein1-Acylglycerophosphocholine O-Acyltransferase protein1-Acylglycerophosphoethanolamine O-Acyltransferase protein1-Acylglycerophosphoserine O-Acyltransferase Mboat1 proteinLysophosphatidylserine Acyltransferase proteinLpsat proteinLyso-Ps Acyltransferase proteinMembrane-Bound O-Acyltransferase Domain-Containing Protein 1 proteinO-Acyltransferase Domain-Containing Protein 1 proteinMBOAT1 proteinOACT1 protein |
Information sourced from Uniprot.org