| Applications: | Immunodepletion/Immunocompetition |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description : | MAP3K4 Blocking Peptide for STJ501674 is synthetically produced from the 1558-1608 sequence and is suitable for use in western blot applications. |
| Formulation: | Liquid form at 2.5mg/ml concentration in PBS. Up to 5% DMSO can be added. Orders with >1mg can be supplied in lyophilized powder form, or in buffer of choice. |
| Storage Instruction: | Store at-20°C for long term storage. Avoid freeze-thaw cycles. |
| Gene Symbol: | MAP3K4 |
| Gene ID: | 4216 |
| Uniprot ID: | M3K4_HUMAN |
| Immunogen Region: | 1558-1608 |
| Specificity: | This blocking peptide is recommended for use in combination with MAP3K4 antibody, STJ501674 |
| Immunogen: | Synthetic peptide taken within amino acid region 1558-1608 on human MAP3K4 protein. |
| Tissue Specificity | Expressed at high levels in heart, placenta, skeletal muscle and pancreas, and at lower levels in other tissues. |
| Function | Component of a protein kinase signal transduction cascade. Activates the CSBP2, P38 and JNK MAPK pathways, but not the ERK pathway. Specifically phosphorylates and activates MAP2K4 and MAP2K6. |
| Peptide Name | Mitogen-Activated Protein Kinase Kinase Kinase 4Map Three Kinase 1Mapk/Erk Kinase Kinase 4Mek Kinase 4Mekk 4 |
| Cellular Localisation | CytoplasmPerinuclear RegionLocalized In Perinuclear Vesicular-Like StructuresProbably Golgi-Associated Vesicles |
| Alternative Peptide Names | Mitogen-Activated Protein Kinase Kinase Kinase 4 proteinMap Three Kinase 1 proteinMapk/Erk Kinase Kinase 4 proteinMek Kinase 4 proteinMekk 4 proteinMAP3K4 proteinKIAA0213 proteinMAPKKK4 proteinMEKK4 proteinMTK1 protein |
Information sourced from Uniprot.org