Function | Pseudokinase which, in complex with CAB39/MO25 (CAB39/MO25alpha or CAB39L/MO25beta), binds to and activates STK11/LKB1. Adopts a closed conformation typical of active protein kinases and binds STK11/LKB1 as a pseudosubstrate, promoting conformational change of STK11/LKB1 in an active conformation. |
Peptide Name | Ste20-Related Kinase Adapter Protein AlphaStrad AlphaSte20-Related Adapter ProteinSerologically Defined Breast Cancer Antigen Ny-Br-96 |
Database Links | Reactome: R-HSA-380972 |
Cellular Localisation | NucleusCytoplasm |
Alternative Peptide Names | Ste20-Related Kinase Adapter Protein Alpha proteinStrad Alpha proteinSte20-Related Adapter Protein proteinSerologically Defined Breast Cancer Antigen Ny-Br-96 proteinSTRADA proteinLYK5 proteinSTRAD protein |
Information sourced from Uniprot.org