Applications: |
Immunodepletion/Immunocompetition |
Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Short Description: |
ITPR2 Blocking Peptide for STJ501515 is synthetically produced from the 100-150 sequence and is suitable for use in western blot applications. |
Formulation: |
Liquid form at 2.5mg/ml concentration in PBS. Up to 5% DMSO can be added. Orders with >1mg can be supplied in lyophilized powder form, or in buffer of choice. |
Storage Instruction: |
Store at-20°C for long term storage. Avoid freeze-thaw cycles. |
Gene Symbol: |
Itpr2 |
Gene ID: |
81678 |
Uniprot ID: |
ITPR2_RAT |
Immunogen Region: |
100-150 |
Specificity: |
This blocking peptide is recommended for use in combination with ITPR2 antibody, STJ501515 |
Immunogen: |
Synthetic peptide taken within amino acid region 100-150 on rat Inosital 1, 4, 5-triphosphate receptor type 2 protein. |
Post Translational Modifications | Phosphorylation by cAMP-dependent PKA on Ser-937 increases calcium release. |
Function | Receptor for inositol 1,4,5-trisphosphate, a second messenger that mediates the release of intracellular calcium. This release is regulated by cAMP both dependently and independently of PKA. |
Peptide Name | Inositol 1 -4 -5-Trisphosphate Receptor Type 2Ip3 Receptor Isoform 2Ip3r 2Insp3r2Type 2 Inositol 1 -4 -5-Trisphosphate ReceptorType 2 Insp3 Receptor |
Database Links | Reactome: R-RNO-114508Reactome: -RNO-139853Reactome: -RNO-381676Reactome: -RNO-5578775Reactome: -RNO-983695 |
Cellular Localisation | Endoplasmic Reticulum MembraneMulti-Pass Membrane Protein |
Alternative Peptide Names | Inositol 1 -4 -5-Trisphosphate Receptor Type 2 proteinIp3 Receptor Isoform 2 proteinIp3r 2 proteinInsp3r2 proteinType 2 Inositol 1 -4 -5-Trisphosphate Receptor proteinType 2 Insp3 Receptor proteinItpr2 protein |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance