| Applications: |
Immunodepletion/Immunocompetition |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Indoleamine 2 3-dioxygenase 2 Blocking Peptide is synthetically produced from the 370-420 sequence and is suitable for use in western blot applications. |
| Formulation: |
Liquid form at 2.5mg/ml concentration in PBS. Up to 5% DMSO can be added. Orders with >1mg can be supplied in lyophilized powder form, or in buffer of choice. |
| Storage Instruction: |
Store at-20°C for long term storage. Avoid freeze-thaw cycles. |
| Gene Symbol: |
IDO2 |
| Gene ID: |
169355 |
| Uniprot ID: |
I23O2_HUMAN |
| Immunogen Region: |
370-420 |
| Immunogen: |
Synthetic peptide taken within amino acid region 370-420 on human Indoleamine 2, 3-dioxygenase 2 protein. |
| Tissue Specificity | Detected in liver, small intestine, spleen, placenta, thymus, lung, brain, kidney, and colon. Also expressed at low level in testis and thyroid. Not expressed in the majority of human tumor samples (>99%). |
| Function | Catalyzes the first and rate limiting step of the catabolism of the essential amino acid tryptophan along the kynurenine pathway. Involved in immune regulation. May not play a significant role in tryptophan-related tumoral resistance. |
| Peptide Name | Indoleamine 2 -3-Dioxygenase 2Ido-2Indoleamine 2 -3-Dioxygenase-Like Protein 1Indoleamine-Pyrrole 2 -3-Dioxygenase-Like Protein 1 |
| Database Links | Reactome: R-HSA-71240 |
| Alternative Peptide Names | Indoleamine 2 -3-Dioxygenase 2 proteinIdo-2 proteinIndoleamine 2 -3-Dioxygenase-Like Protein 1 proteinIndoleamine-Pyrrole 2 -3-Dioxygenase-Like Protein 1 proteinIDO2 proteinINDOL1 protein |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
