Post Translational Modifications | Proteolytically cleaved before the transmembrane segment to yield the secreted ectodomain incorporated in the zona pellucida. O-glycosylated. |
Function | Component of the zona pellucida, an extracellular matrix surrounding oocytes which mediates sperm binding, induction of the acrosome reaction and prevents post-fertilization polyspermy. The zona pellucida is composed of 3 to 4 glycoproteins, ZP1, ZP2, ZP3, and ZP4. ZP1 ensures the structural integrity of the zona pellucida. |
Protein Name | Zona Pellucida Sperm-Binding Protein 1Zona Pellucida Glycoprotein 1Zp-1 Cleaved Into - Processed Zona Pellucida Sperm-Binding Protein 1 |
Database Links | Reactome: R-HSA-2534343 |
Cellular Localisation | Processed Zona Pellucida Sperm-Binding Protein 1: Zona PellucidaCell MembraneSingle-Pass Type I Membrane Protein |
Alternative Protein Names | Zona Pellucida Sperm-Binding Protein 1 proteinZona Pellucida Glycoprotein 1 proteinZp-1 Cleaved Into - Processed Zona Pellucida Sperm-Binding Protein 1 proteinZP1 protein |
Information sourced from Uniprot.org