Human ZNF263 protein (Recombinant) (N-His) (STJP010639)

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STJP010639
€410.63 - €1,796.88
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Host: E. coli
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description : Recombinant-Human ZNF263-N-His protein was developed from e. coli and has a target region of N-His. For use in research applications.
Formulation: Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Storage Instruction: Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at-20 to-80°C for twelve months from the date of receipt.
Gene Symbol: ZNF263
Gene ID: 10127
Uniprot ID: ZN263_HUMAN
Immunogen Region: Lys375-Tyr546
Immunogen: Homo sapiens (Human)
Post Translational Modifications Ubiquitinated, leading to proteasomal degradation.
Function Transcription factor that binds to the consensus sequence 5'-TCCTCCC-3' and acts as a transcriptional repressor. Binds to the promoter region of SIX3 and recruits other proteins involved in chromatin modification and transcriptional corepression, resulting in methylation of the promoter and transcriptional repression. Acts as a transcriptional repressor of HS3ST1 and HS3ST3A1 via binding to gene promoter regions.
Protein Name Zinc Finger Protein 263
Zinc Finger Protein Fpm315
Zinc Finger Protein With Krab And Scan Domains 12
Database Links Reactome: R-HSA-212436
Cellular Localisation Nucleus
Alternative Protein Names Zinc Finger Protein 263 protein
Zinc Finger Protein Fpm315 protein
Zinc Finger Protein With Krab And Scan Domains 12 protein
ZNF263 protein
FPM315 protein
ZKSCAN12 protein

Information sourced from Uniprot.org

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