Tissue Specificity | Highly expressed in pancreatic cancer tissues (at protein levels). Also expressed in the placenta and colon and ovarian cancer tumors. |
Post Translational Modifications | N-glycosylated. |
Function | Plays an important role in pancreatic tumor progression and metastasis. Promotes pancreatic cancer cells migration and invasion through the TLR4/MyD88/NF-kaapaB signaling pathway, without the involvement of the TLR4/TRIF pathway. |
Protein Name | Pancreatic Adenocarcinoma Up-Regulated FactorZymogen Granule Protein 16 Homolog B |
Database Links | |
Cellular Localisation | SecretedCytoplasmCell MembraneApicolateral Cell MembraneCo-Localizes With Tlr4 At The Cell Membrane Of Pancreatic Cancer Cells |
Alternative ELISA Names | Pancreatic Adenocarcinoma Up-Regulated Factor ELISA kitZymogen Granule Protein 16 Homolog B ELISA kitZG16B ELISA kitPAUF ELISA kitUNQ773 ELISA kitPRO1567 ELISA kit |
output | |
Information sourced from Uniprot.org