Human YJEFN3 protein (Recombinant) (N-His) (STJP003118)

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STJP003118
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Host: E. coli
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description : Recombinant-Human YJEFN3-N-His protein was developed from e. coli and has a target region of N-His. For use in research applications.
Formulation: Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Storage Instruction: Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at-20 to-80°C for twelve months from the date of receipt.
Gene Symbol: YJEFN3
Gene ID: 374887
Uniprot ID: YJEN3_HUMAN
Immunogen Region: Met1-Leu299
Immunogen: Homo sapiens (Human)
Function May accelerate cholesterol efflux from endothelial cells to high-density lipoprotein (HDL) and thereby regulates angiogenesis. May orchestrate hematopoietic stem and progenitor cell emergence from the hemogenic endothelium, a type of specialized endothelium manifesting hematopoietic potential. YJEFN3-mediated cholesterol efflux activates endothelial SREBF2, the master transcription factor for cholesterol biosynthesis, which in turn transactivates NOTCH and promotes hematopoietic stem and progenitor cell emergence. May play a role in spermiogenesis and oogenesis.
Protein Name Yjef N-Terminal Domain-Containing Protein 3
Yjef_n3
Hyjef_n3
Apoa-I-Binding Protein 2
Alternative Protein Names Yjef N-Terminal Domain-Containing Protein 3 protein
Yjef_n3 protein
Hyjef_n3 protein
Apoa-I-Binding Protein 2 protein
YJEFN3 protein
AIBP2 protein

Information sourced from Uniprot.org

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