Human XYLT1 protein (Recombinant) (N-His) (STJP005662)

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STJP005662
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Host: E. coli
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description : Recombinant-Human XYLT1-N-His protein was developed from e. coli and has a target region of N-His. For use in research applications.
Formulation: Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Storage Instruction: Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at-20 to-80°C for twelve months from the date of receipt.
Gene Symbol: XYLT1
Gene ID: 64131
Uniprot ID: XYLT1_HUMAN
Immunogen Region: Gly773-Val910
Immunogen: Homo sapiens (Human)
Post Translational Modifications Contains 7 disulfide bonds. N-glycosylated.
Function Catalyzes the first step in the biosynthesis of chondroitin sulfate and dermatan sulfate proteoglycans, such as DCN. Transfers D-xylose from UDP-D-xylose to specific serine residues of the core protein. Required for normal embryonic and postnatal skeleton development, especially of the long bones. Required for normal maturation of chondrocytes during bone development, and normal onset of ossification.
Protein Name Xylosyltransferase 1
Peptide O-Xylosyltransferase 1
Xylosyltransferase I
Xt-I
Xylt-I
Database Links Reactome: R-HSA-1971475
Cellular Localisation Golgi Apparatus Membrane
Single-Pass Type Ii Membrane Protein
Secreted
Detected Predominantly In The Golgi Apparatus
Alternative Protein Names Xylosyltransferase 1 protein
Peptide O-Xylosyltransferase 1 protein
Xylosyltransferase I protein
Xt-I protein
Xylt-I protein
XYLT1 protein
XT1 protein

Information sourced from Uniprot.org

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