Tissue Specificity | Moderately expressed in fetal brain, weakly expressed in fetal lung and kidney, and faintly expressed in adult brain, lung and prostate. |
Post Translational Modifications | Palmitoleoylation is required for efficient binding to frizzled receptors. Depalmitoleoylation leads to Wnt signaling pathway inhibition. |
Function | Ligand for members of the frizzled family of seven transmembrane receptors that functions in the canonical Wnt/beta-catenin signaling pathway. Required for normal fusion of the chorion and the allantois during placenta development. Required for central nervous system (CNS) angiogenesis and blood-brain barrier regulation. |
Protein Name | Protein Wnt-7b |
Database Links | Reactome: R-HSA-3238698Reactome: R-HSA-373080 |
Cellular Localisation | SecretedExtracellular SpaceExtracellular Matrix |
Alternative ELISA Names | Protein Wnt-7b ELISA kitWNT7B ELISA kit |
output | |
Information sourced from Uniprot.org