Applications: |
ELISA |
Reactivity: |
Human |
Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Sensitivity: |
0.062ng/mL |
Detection Limit: |
0.156-10ng/mL |
Short Description: |
This WNT2 Sandwich ELISA Kit, Ready-To-Use is an in-vitro enzyme-linked immunosorbent assay for the measurement of samples in human tissue homogenates, cell lysates or other biological fluids.. |
Storage Instruction: |
The whole kit may be stored at-20°C for up to 12 months from receipt. An unopened kit may be stored in the fridge at 2-8°C for up to 6 months. Once opened store individual kit contents according to components table provided with the kit. |
Assay Time: |
3 hrs |
Gene Symbol: |
WNT2 |
Gene ID: |
7472 |
Uniprot ID: |
WNT2_HUMAN |
Immunogen Region: |
Ready-To-Use |
Sample Type: |
tissue homogenates, cell lysates or other biological fluids. |
Tissue Specificity | Expressed in brain in the thalamus, in fetal and adult lung and in placenta. |
Post Translational Modifications | Palmitoleoylation is required for efficient binding to frizzled receptors. Depalmitoleoylation leads to Wnt signaling pathway inhibition. |
Function | Ligand for members of the frizzled family of seven transmembrane receptors. Functions in the canonical Wnt signaling pathway that results in activation of transcription factors of the TCF/LEF family. Functions as a upstream regulator of FGF10 expression. Plays an important role in embryonic lung development. May contribute to embryonic brain development by regulating the proliferation of dopaminergic precursors and neurons. |
Protein Name | Protein Wnt-2Int-1-Like Protein 1Int-1-Related ProteinIrp |
Database Links | Reactome: R-HSA-3238698Reactome: R-HSA-373080 |
Cellular Localisation | SecretedExtracellular SpaceExtracellular Matrix |
Alternative ELISA Names | Protein Wnt-2 ELISA kitInt-1-Like Protein 1 ELISA kitInt-1-Related Protein ELISA kitIrp ELISA kitWNT2 ELISA kitINT1L1 ELISA kitIRP ELISA kit |
output | |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance