Human WBP2 protein (Recombinant) (N-His) (STJP007841)
SPECIFICATIONS
HostE.coli
ImmunogenHomo sapiens (Human)
General Information
| Short Description | Recombinant-Human WBP2-N-His protein was developed from e.coli for the region N-His. For use in research applications. |
| Applications | ELISA/Immunogen/SDS-PAGE/WB |
| Host | E.coli |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Dilution Range | Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details. |
| Formulation | Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol. |
| Storage Instruction | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at-20 to-80°C for twelve months from the date of receipt. |
Target Information
| Gene Symbol | WBP2 |
| Gene ID | 23558 |
| Uniprot ID | WBP2_HUMAN |
| Immunogen | Homo sapiens (Human) |
| Immunogen Region | Met1-Gly136 |
Additional Info
| Post Translational Modifications | Phosphorylated in repsonse to EGF as well as estrogen and progesterone hormones. Tyr-192 and Tyr-231 are phosphorylated by YES and SRC inducing nuclear translocation. |
| Function | Acts as a transcriptional coactivator of estrogen and progesterone receptors (ESR1 and PGR) upon hormone activation. In presence of estrogen, binds to ESR1-responsive promoters. Synergizes with YAP1 to enhance PGR activity. Modulates expression of post-synaptic scaffolding proteins via regulation of ESR1, ESR2 and PGR. |
| Protein Name | Ww Domain-Binding Protein 2Wbp-2 |
| Database Links | |
| Cellular Localisation | CytoplasmNucleusTranslocates From Cytoplasm To Nucleus When Phosphorylated |
| Alternative Protein Names | Ww Domain-Binding Protein 2 proteinWbp-2 proteinWBP2 protein |
Information sourced from Uniprot.org