Human WARS1 protein (Recombinant) (N-His) (STJP014452)
SPECIFICATIONS
HostE.coli
ConjugationUnconjugated
ImmunogenHomo sapiens (Human)
General Information
| Short Description | Recombinant-Human WARS1-N-His protein was developed from e.coli and has a target region of N-His. For use in research applications. |
| Applications | ELISA/WB |
| Host | E.coli |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Conjugation | Unconjugated |
| Dilution Range | Reconstitute in sterile water for a stock solution. |
| Formulation | Lyophilized from a 0.22 Mu m filtered solution in 20mM PB, 8% Trehalose, 4% Mannitol, 50mM NaCl, 0.05% Tween 80, pH 7.5. |
| Storage Instruction | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for one week. Store at-20 to-80°C for twelve months from the date of receipt. |
| Endotoxin | < 1 EU/µg as determined by LAL test. |
Target Information
| Gene Symbol | WARS1 |
| Gene ID | 7453 |
| Uniprot ID | SYWC_HUMAN |
| Immunogen | Homo sapiens (Human) |
| Immunogen Region | Met1-Gln471 |
Additional Info
| Function | Catalyzes the attachment of tryptophan to tRNA(Trp) in a two-step reaction: tryptophan is first activated by ATP to form Trp-AMP and then transferred to the acceptor end of the tRNA(Trp). Isoform 1: Has no angiostatic activity. T2-TrpRS: Possesses an angiostatic activity but has no aminoacylation activity. Inhibits fluid shear stress-activated responses of endothelial cells. Regulates ERK, Akt, and eNOS activation pathways that are associated with angiogenesis, cytoskeletal reorganization and shear stress-responsive gene expression. Isoform 2: Has an angiostatic activity. |
| Protein Name | Tryptophan--Trna Ligase - CytoplasmicInterferon-Induced Protein 53Ifp53Tryptophanyl-Trna SynthetaseTrprsHwrs Cleaved Into - T1-Trprs - T2-Trprs |
| Database Links | Reactome: R-HSA-379716 |
| Cellular Localisation | Cytoplasm |
| Alternative Protein Names | Tryptophan--Trna Ligase - Cytoplasmic proteinInterferon-Induced Protein 53 proteinIfp53 proteinTryptophanyl-Trna Synthetase proteinTrprs proteinHwrs Cleaved Into - T1-Trprs - T2-Trprs proteinWARS1 proteinIFI53 proteinWARS proteinWRS protein |
Information sourced from Uniprot.org