Human WARS1 protein (Recombinant) (N-His) (STJP004373)

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STJP004373
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Host: E. coli
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description : Recombinant-Human WARS1-N-His protein was developed from e. coli and has a target region of N-His. For use in research applications.
Formulation: Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Storage Instruction: Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at-20 to-80°C for twelve months from the date of receipt.
Gene Symbol: WARS1
Gene ID: 7453
Uniprot ID: SYWC_HUMAN
Immunogen Region: Phe247-Lys458
Immunogen: Homo sapiens (Human)
Function Catalyzes the attachment of tryptophan to tRNA(Trp) in a two-step reaction: tryptophan is first activated by ATP to form Trp-AMP and then transferred to the acceptor end of the tRNA(Trp). Isoform 1: Has no angiostatic activity. T2-TrpRS: Possesses an angiostatic activity but has no aminoacylation activity. Inhibits fluid shear stress-activated responses of endothelial cells. Regulates ERK, Akt, and eNOS activation pathways that are associated with angiogenesis, cytoskeletal reorganization and shear stress-responsive gene expression. Isoform 2: Has an angiostatic activity.
Protein Name Tryptophan--Trna Ligase - Cytoplasmic
Interferon-Induced Protein 53
Ifp53
Tryptophanyl-Trna Synthetase
Trprs
Hwrs Cleaved Into - T1-Trprs - T2-Trprs
Database Links Reactome: R-HSA-379716
Cellular Localisation Cytoplasm
Alternative Protein Names Tryptophan--Trna Ligase - Cytoplasmic protein
Interferon-Induced Protein 53 protein
Ifp53 protein
Tryptophanyl-Trna Synthetase protein
Trprs protein
Hwrs Cleaved Into - T1-Trprs - T2-Trprs protein
WARS1 protein
IFI53 protein
WARS protein
WRS protein

Information sourced from Uniprot.org

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