| Host: | HEK293 cells |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Conjugation: | Unconjugated |
| Formulation: | Lyophilised from a 0.22 Mu m filtered solution of PBS, pH 7.4. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Determination Method: | < 0.1 EU/Mu g of the protein by LAL method. |
| Gene Symbol: | WFDC2 |
| Gene ID: | 10406 |
| Uniprot ID: | WFDC2_HUMAN |
| Immunogen Region: | Glu31-Phe124 |
| Immunogen: | Recombinant Human WAP5/WFDC2/HE4 Protein is produced by HEK293 expression system. The target protein is expressed with sequence (Glu31-Phe124) of human WAP5/WFDC2/HE4 (Accession #NP_006094.3) fused with a 6×His tag at the C-terminus. |
| Immunogen Sequence: | EKTGVCPELQADQNCTQECV SDSECADNLKCCSAGCATFC SLPNDKEGSCPQVNINFPQL GLCRDQCQVDSQCPGQMKCC RNGCGKVSCVTPNF |
| Tissue Specificity | Expressed in a number of normal tissues, including male reproductive system, regions of the respiratory tract and nasopharynx. Highly expressed in a number of tumors cells lines, such ovarian, colon, breast, lung and renal cells lines. Initially described as being exclusively transcribed in the epididymis. |
| Function | Broad range protease inhibitor. |
| Protein Name | Wap Four-Disulfide Core Domain Protein 2Epididymal Secretory Protein E4Major Epididymis-Specific Protein E4Putative Protease Inhibitor Wap5 |
| Database Links | Reactome: R-HSA-9830364 |
| Cellular Localisation | Secreted |
| Alternative Protein Names | Wap Four-Disulfide Core Domain Protein 2 proteinEpididymal Secretory Protein E4 proteinMajor Epididymis-Specific Protein E4 proteinPutative Protease Inhibitor Wap5 proteinWFDC2 proteinHE4 proteinWAP5 protein |
Information sourced from Uniprot.org
