Human VTCN1/B7-H4 protein (Recombinant-Active) (C-Fc) (STJP012700)

Name: Human VTCN1/B7-H4 protein (Recombinant-Active) (C-Fc) (STJP012700)
SKU: STJP012700-100
Price: 575.5 GBP
Availability: InStock

⇓ Datasheet ⇓ SDS

SPECIFICATIONS

HostMammalian Cells

ConjugationUnconjugated

ImmunogenHomo sapiens (Human)

STJP012700-100

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Short Description	Recombinant-Active-Human VTCN1/B7-H4-C-Fc protein was developed from mammalian cells and has a target region of C-Fc. For use in research applications.
Applications	ELISA/WB
Host	Mammalian Cells
Note	STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.

Conjugation	Unconjugated
Dilution Range	Reconstitute in sterile water for a stock solution.
Formulation	Lyophilized from a 0.22 Mu m filtered solution in PBS, pH 7.4.
Storage Instruction	Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for one week. Store at-20 to-80°C for twelve months from the date of receipt.
Endotoxin	< 1 EU/µg as determined by LAL test.

Post Translational Modifications	N-glycosylated.
Function	Negatively regulates T-cell-mediated immune response by inhibiting T-cell activation, proliferation, cytokine production and development of cytotoxicity. When expressed on the cell surface of tumor macrophages, plays an important role, together with regulatory T-cells (Treg), in the suppression of tumor-associated antigen-specific T-cell immunity. Involved in promoting epithelial cell transformation.
Protein Name	V-Set Domain-Containing T-Cell Activation Inhibitor 1 B7 Homolog 4 B7-H4 B7h.5 Immune Costimulatory Protein B7-H4 Protein B7s1 T-Cell Costimulatory Molecule B7x
Database Links
Cellular Localisation	Cell Membrane Single-Pass Type I Membrane Protein Expressed At The Cell Surface A Soluble Form Has Also Been Detected
Alternative Protein Names	V-Set Domain-Containing T-Cell Activation Inhibitor 1 protein B7 Homolog 4 protein B7-H4 protein B7h.5 protein Immune Costimulatory Protein B7-H4 protein Protein B7s1 protein T-Cell Costimulatory Molecule B7x protein VTCN1 protein B7H4 protein UNQ659 protein PRO1291 protein

Information sourced from Uniprot.org