| Short Description : | Recombinant-Human VSIG4-C-His protein was developed in hek293 cells using the region Arg20-Pro283. For use in research applications. |
| Host: | HEK293 cells |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Conjugation: | Unconjugated |
| Formulation: | Lyophilised from a 0.22 Mu m filtered solution of PBS, pH 7.4. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Determination Method: | <0.1 EU/Mu g |
| Gene Symbol: | VSIG4 |
| Gene ID: | 11326 |
| Uniprot ID: | VSIG4_HUMAN |
| Immunogen: | Recombinant Human VSIG4 Protein is produced by HEK293 cells expression system. The target protein is expressed with sequence (Arg20-Pro283) of human VSIG4 (Accession #NP_009199.1) fused with a 6×His tag at the C-terminus. |
| Immunogen Region: | Arg20-Pro283 |
| Immunogen Sequence: | RPILEVPESVTGPWKGDVNL PCTYDPLQGYTQVLVKWLVQ RGSDPVTIFLRDSSGDHIQQ AKYQGRLHVSHKVPGDVSLQ LSTLEMDDRSHYTCEVTWQT PDGNQVVRDKITELRVQKLS VSKPTVTTGSGYGFTVPQGM RISLQCQARGSPPISYIWYK QQTNNQEPIKVATLSTLLFK PAVIADSGSYFCTAKGQVGS EQHSDIVKFVVKDSSKLLKT KTEAPTTMTYPLKATSTVK |
| Function | Phagocytic receptor, strong negative regulator of T-cell proliferation and IL2 production. Potent inhibitor of the alternative complement pathway convertases. |
| Protein Name | V-Set And Immunoglobulin Domain-Containing Protein 4Protein Z39ig |
| Database Links | |
| Cellular Localisation | MembraneSingle-Pass Type I Membrane Protein |
| Alternative Protein Names | V-Set And Immunoglobulin Domain-Containing Protein 4 proteinProtein Z39ig proteinVSIG4 proteinCRIg proteinZ39IG proteinUNQ317 proteinPRO362 protein |
Information sourced from Uniprot.org
