| Host: |
HEK293 cells |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Formulation: |
Lyophilised from a 0.22 Mu m filtered solution of PBS, pH 7.4. |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Determination Method: |
< 0.1 EU/Mu g of the protein by LAL method. |
| Gene Symbol: |
VSIG4 |
| Gene ID: |
11326 |
| Uniprot ID: |
VSIG4_HUMAN |
| Immunogen Region: |
Arg20-Pro283 |
| Immunogen: |
Recombinant Human VSIG4 Protein is produced by HEK293 expression system. The target protein is expressed with sequence (Arg20-Pro283) of human VSIG4 (Accession #NP_009199.1) fused with an Fc, 6×His tag at the C-terminus. |
| Immunogen Sequence: |
RPILEVPESVTGPWKGDVNL PCTYDPLQGYTQVLVKWLVQ RGSDPVTIFLRDSSGDHIQQ AKYQGRLHVSHKVPGDVSLQ LSTLEMDDRSHYTCEVTWQT PDGNQVVRDKITELRVQKLS VSKPTVTTGSGYGFTVPQGM RISLQCQARGSPPISYIWYK QQTNNQEPIKVATLSTLLFK PAVIADSGSYFCTAKGQVGS EQHSDIVKFVVKDSSKLLKT KTEAPTTMTYPLKATSTVK |
| Tissue Specificity | Abundantly expressed in several fetal tissues. In adult tissues, highest expression in lung and placenta. Expressed in resting macrophages. |
| Function | Phagocytic receptor, strong negative regulator of T-cell proliferation and IL2 production. Potent inhibitor of the alternative complement pathway convertases. |
| Protein Name | V-Set And Immunoglobulin Domain-Containing Protein 4Protein Z39ig |
| Cellular Localisation | MembraneSingle-Pass Type I Membrane Protein |
| Alternative Protein Names | V-Set And Immunoglobulin Domain-Containing Protein 4 proteinProtein Z39ig proteinVSIG4 proteinCRIg proteinZ39IG proteinUNQ317 proteinPRO362 protein |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
