| Host: | HEK293 cells |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Formulation: | Lyophilised from a 0.22 Mu m filtered solution of PBS, pH 7.4. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Determination Method: | <0.1 EU/Mu g |
| Immunoreactivity: | Measured by its binding ability in a functional ELISA. Immobilized Human VISTA at 5 Mu g/mL (100 Mu L/well) can bind Biotinylated Human VSIG3/IgSF11 with a linear range of 0.02-2.03 Mu g/mL. |
| Gene Symbol: | IGSF11 |
| Gene ID: | 152404 |
| Uniprot ID: | IGS11_HUMAN |
| Immunogen: | Recombinant Human VSIG3/IgSF11 Protein is produced by HEK293 cells expression system. The target protein is expressed with sequence (Leu23-Gly241) of human VSIG3/IGSF11 (Accession #NP_001015887.1) fused with a Fc, Avi tag at the C-terminus. |
| Immunogen Sequence: | LEVSESPGSIQVARGQPAVL PCTFTTSAALINLNVIWMVT PLSNANQPEQVILYQGGQMF DGAPRFHGRVGFTGTMPATN VSIFINNTQLSDTGTYQCLV NNLPDIGGRNIGVTGLTVLV PPSAPHCQIQGSQDIGSDVI LLCSSEEGIPRPTYLWEKLD NTLKLPPTATQDQVQGTVTI RNISALSSGLYQCVASNAIG TSTCLLDLQVISPQPRNIG |
| Post Translational Modifications | N-glycosylated. |
| Function | Functions as a cell adhesion molecule through homophilic interaction. Stimulates cell growth. |
| Protein Name | Immunoglobulin Superfamily Member 11Igsf11Brain And Testis-Specific Immunoglobulin Superfamily ProteinBt-IgsfV-Set And Immunoglobulin Domain-Containing Protein 3 |
| Cellular Localisation | Cell MembraneSingle-Pass Type I Membrane Protein |
| Alternative Protein Names | Immunoglobulin Superfamily Member 11 proteinIgsf11 proteinBrain And Testis-Specific Immunoglobulin Superfamily Protein proteinBt-Igsf proteinV-Set And Immunoglobulin Domain-Containing Protein 3 proteinIGSF11 proteinBTIGSF proteinCXADRL1 proteinVSIG3 protein |
Information sourced from Uniprot.org