| Tissue Specificity | In lung, HT-29 colonic epithelial cells, Raji B-lymphoblasts. Lesser extent in brain, heart, kidney, liver and placenta. Not expressed in CD4+ or CD8+ T-cells. Expressed in the T-cell lines HARRIS, HuT 78, Jurkat and SUP-T1, but not in the T-cell lines Peer, MOLT-4, HSB and YT. |
| Post Translational Modifications | |
| Function | This is a receptor for VIP. The activity of this receptor is mediated by G proteins which activate adenylyl cyclase. The affinity is VIP = PACAP-27 > PACAP-38. |
| Protein Name | Vasoactive Intestinal Polypeptide Receptor 1Vip-R-1Pituitary Adenylate Cyclase-Activating Polypeptide Type Ii ReceptorPacap Type Ii ReceptorPacap-R-2Pacap-R2Vpac1 |
| Database Links | Reactome: R-HSA-418555Reactome: R-HSA-420092 |
| Cellular Localisation | Cell MembraneMulti-Pass Membrane Protein |
| Alternative ELISA Names | Vasoactive Intestinal Polypeptide Receptor 1 ELISA kitVip-R-1 ELISA kitPituitary Adenylate Cyclase-Activating Polypeptide Type Ii Receptor ELISA kitPacap Type Ii Receptor ELISA kitPacap-R-2 ELISA kitPacap-R2 ELISA kitVpac1 ELISA kitVIPR1 ELISA kit |
| output | |
Information sourced from Uniprot.org
