Human VEGF-D (Vascular Endothelial Growth Factor D) Antibody Pair (STJAP00211)
General Information
| Short Description | This VEGF-D antibody pair contains complimentary capture and detection antibodies, which work together under the principals of the Sandwich ELISA. |
| Applications | ELISA |
| Host | Goat/Rabbit |
| Reactivity | Human |
| Note | FOR SCIENTIFIC EDUCATIONAL RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR OTHER MEDICAL APPLICATIONS. |
Product Properties
| Clonality | Polyclonal/Polyclonal |
| Conjugation | Unconjugated/Biotin |
| Concentration | 0.5 mg/mL |
| Purification | Capture Purification: Antigen Affinity.Detection Purification: Protein A & Antigen Affinity. |
| Formulation | Capture Buffer: PBS with 0.04% Proclin 300, 50% glycerol, pH 7.4.Detection Buffer: PBS with 0.04% Proclin 300, 50% glycerol, pH 7.4. |
| Storage Instruction | Store at-20°C for the long term, and avoid freeze-thaw cycles. |
Target Information
| Gene Symbol | VEGFD |
| Gene ID | 2277 |
| Uniprot ID | VEGFD_HUMAN |
| Immunogen | Capture immunogen: Recombinant Human VEGF-D protein.Detection Immunogen: Recombinant Human VEGF-D protein. |
Additional Info
| Post Translational Modifications | Undergoes a complex proteolytic maturation which generates a variety of processed secreted forms with increased activity toward VEGFR-3 and VEGFR-2. VEGF-D first form an antiparallel homodimer linked by disulfide bonds before secretion. The fully processed VEGF-D is composed mostly of two VEGF homology domains (VHDs) bound by non-covalent interactions. |
| Function | Growth factor active in angiogenesis, lymphangiogenesis and endothelial cell growth, stimulating their proliferation and migration and also has effects on the permeability of blood vessels. May function in the formation of the venous and lymphatic vascular systems during embryogenesis, and also in the maintenance of differentiated lymphatic endothelium in adults. Binds and activates VEGFR-2 (KDR/FLK1) and VEGFR-3 (FLT4) receptors. |
| Protein Name | Vascular Endothelial Growth Factor DVegf-DC-Fos-Induced Growth FactorFigf |
| Database Links | Reactome: R-HSA-114608Reactome: R-HSA-194313Reactome: R-HSA-195399 |
| Cellular Localisation | Secreted |
| Alternative Antibody Pair Names | Vascular Endothelial Growth Factor D antibody pairVegf-D antibody pairC-Fos-Induced Growth Factor antibody pairFigf antibody pairVEGFD antibody pairFIGF antibody pair |
Information sourced from Uniprot.org
Citations
Product Review
Frequently Asked Questions
Common questions about Human VEGF-D (Vascular Endothelial Growth Factor D) Antibody Pair (STJAP00211)
This antibody pair detects human VEGF-D (Vascular Endothelial Growth Factor D), corresponding to UniProt accession O43915. Reactivity is confirmed for human samples only.
The capture antibody is an unconjugated goat polyclonal antibody, and the detection antibody is a biotin-conjugated rabbit polyclonal antibody. Both components are supplied at 0.5 mg/mL in PBS containing 0.04% Proclin 300 and 50% glycerol at pH 7.4.
This antibody pair has been validated for use in ELISA. No other assay formats are listed in the product specifications.
Both the capture and detection antibodies were raised against recombinant human VEGF-D protein. The capture antibody was purified by antigen affinity, while the detection antibody was purified by Protein A and antigen affinity methods.
Both components should be stored at -20 degrees Celsius for long-term storage. Freeze-thaw cycles should be avoided to maintain antibody integrity.
Orders typically arrive within 1 to 2 weeks, and often sooner depending on your location. If your timeline is critical, please contact us before ordering and we can advise on current lead times.
This product is shipped on gel ice packs to maintain integrity during transit. Priority shipping is used as standard to minimise time in transit.
A Certificate of Analysis (CoA) is provided with every order. If you do not receive one, please contact us and we will issue it promptly.