Human VDAC3 protein (Recombinant) (N-His) (STJP008097)

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STJP008097
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Host: E.coli
Applications: ELISA/Immunogen/SDS-PAGE/WB
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description : Recombinant-Human VDAC3-N-His protein was developed from e.coli and has a target region of N-His. For use in research applications.
Formulation: Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Dilution Range: Reconstitute in sterile water for a stock solution.
Storage Instruction: Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at-20 to-80°C for twelve months from the date of receipt.
Gene Symbol: VDAC3
Gene ID: 7419
Uniprot ID: VDAC3_HUMAN
Immunogen Region: Met1-Ala283
Immunogen: Homo sapiens (Human)
Post Translational Modifications Ubiquitinated by PRKN during mitophagy, leading to its degradation and enhancement of mitophagy. Deubiquitinated by USP30.
Function Non-selective voltage-gated ion channel that mediates the transport of anions and cations through the mitochondrion outer membrane and plasma membrane. Forms a high-conducting channel with a stable open state and a voltage-induced closure with a mild preference for anions over cations. Involved in male fertility and sperm mitochondrial sheath formation.
Protein Name Non-Selective Voltage-Gated Ion Channel Vdac3
Vdac-3
Hvdac3
Outer Mitochondrial Membrane Protein Porin 3
Database Links Reactome: R-HSA-5205685
Reactome: R-HSA-5689880
Reactome: R-HSA-8949215
Cellular Localisation Mitochondrion Outer Membrane
Membrane
May Localize To Non-Mitochondrial Membranes
Alternative Protein Names Non-Selective Voltage-Gated Ion Channel Vdac3 protein
Vdac-3 protein
Hvdac3 protein
Outer Mitochondrial Membrane Protein Porin 3 protein
VDAC3 protein

Information sourced from Uniprot.org

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