| Host: | E. coli |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description : | Recombinant-Human VAV1-N-GST protein was developed from e. coli and has a target region of N-GST. For use in research applications. |
| Formulation: | Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol. |
| Storage Instruction: | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at-20 to-80°C for twelve months from the date of receipt. |
| Gene Symbol: | VAV1 |
| Gene ID: | 7409 |
| Uniprot ID: | VAV_HUMAN |
| Immunogen Region: | Leu426-Arg696 |
| Immunogen: | Homo sapiens (Human) |
| Post Translational Modifications | Phosphorylated on tyrosine residues by HCK in response to IFNG and bacterial lipopolysaccharide (LPS). Phosphorylated by FYN. |
| Function | Couples tyrosine kinase signals with the activation of the Rho/Rac GTPases, thus leading to cell differentiation and/or proliferation. |
| Protein Name | Proto-Oncogene Vav |
| Database Links | Reactome: R-HSA-114604Reactome: R-HSA-1257604Reactome: R-HSA-1433557Reactome: R-HSA-193648Reactome: R-HSA-2029482Reactome: R-HSA-2219530Reactome: R-HSA-2871796Reactome: R-HSA-2871809Reactome: R-HSA-389359Reactome: R-HSA-416482Reactome: R-HSA-4420097Reactome: R-HSA-512988Reactome: R-HSA-5218920Reactome: R-HSA-6811558Reactome: R-HSA-8980692Reactome: R-HSA-9013149Reactome: R-HSA-9013404Reactome: R-HSA-9013408Reactome: R-HSA-9027284Reactome: R-HSA-912631Reactome: R-HSA-9664422Reactome: R-HSA-9679191Reactome: R-HSA-9748787Reactome: R-HSA-983695 |
| Alternative Protein Names | Proto-Oncogene Vav proteinVAV1 proteinVAV protein |
Information sourced from Uniprot.org