| Short Description : | Recombinant-Human VAT1-His-Tag protein was developed from e.coli and has a target region of His-Tag. For use in research applications. |
| Applications: | SDS-PAGE |
| Host: | E.coli |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Concentration: | 0.5 mg/mL |
| Formulation: | Liquid in 20mM Tris-HCl buffer (pH 8.0) containing 1mM DTT, 10% Glycerol, 100mM NaCl |
| Storage Instruction: | For short term storage, keep at +2C to +8C for up to 1 week. For long term storage, aliquot and store at-20C, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | VAT1 |
| Gene ID: | 10493 |
| Uniprot ID: | VAT1_HUMAN |
| Accession Number: | NP_006364 |
| Immunogen: | Human |
| Immunogen Region: | 1-393aa |
| Immunogen Sequence: |
| Tissue Specificity | Expressed in brain. Also expressed in glioblastoma cells. |
| Function | Possesses ATPase activity. Plays a part in calcium-regulated keratinocyte activation in epidermal repair mechanisms. Has no effect on cell proliferation. Negatively regulates mitochondrial fusion in cooperation with mitofusin proteins (MFN1-2). |
| Protein Name | Synaptic Vesicle Membrane Protein Vat-1 Homolog |
| Database Links | Reactome: R-HSA-6798695 |
| Cellular Localisation | CytoplasmMitochondrion Outer MembranePeripheral Membrane ProteinThe Majority Is Localized In The Cytoplasm And A Small Amount Is Associated With Mitochondria |
| Alternative Protein Names | Synaptic Vesicle Membrane Protein Vat-1 Homolog proteinVAT1 protein |
Information sourced from Uniprot.org