| Host: | HEK293 cells |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Formulation: | Lyophilised from a 0.22 Mu m filtered solution of PBS, pH 7.4. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Determination Method: | <1 EU/Mu g |
| Gene Symbol: | VASN |
| Gene ID: | 114990 |
| Uniprot ID: | VASN_HUMAN |
| Immunogen: | Recombinant Human Vasorin/SLIT-like 2/VASN Protein is produced by HEK293 cells expression system. The target protein is expressed with sequence (Met1-Pro575) of human VASN/SLITL2/Vasorin (Accession #NP_612449.2.) fused with a 6×His tag at the C-termi |
| Immunogen Sequence: | MCSRVPLLLPLLLLLALGPG VQGCPSGCQCSQPQTVFCTA RQGTTVPRDVPPDTVGLYVF ENGITMLDAGSFAGLPGLQL LDLSQNQIASLPSGVFQPLA NLSNLDLTANRLHEITNETF RGLRRLERLYLGKNRIRHIQ PGAFDTLDRLLELKLQDNEL RALPPLRLPRLLLLDLSHNS LLALEPGILDTANVEALRLA GLGLQQLDEGLFSRLRNLHD LDVSDNQLERVPPVIRGLR |
| Post Translational Modifications | N-glycosylated. N-glycan heterogeneity at Asn-117: Hex5HexNAc4 (minor), dHex1Hex5HexNAc4 (major), Hex6HexNAc5 (minor) and dHex1Hex6HexNAc5 (minor). |
| Function | May act as an inhibitor of TGF-beta signaling. |
| Protein Name | VasorinProtein Slit-Like 2 |
| Cellular Localisation | MembraneSingle-Pass Type I Membrane ProteinSecreted |
| Alternative Protein Names | Vasorin proteinProtein Slit-Like 2 proteinVASN proteinSLITL2 proteinUNQ314 proteinPRO357 proteinPRO1282 protein |
Information sourced from Uniprot.org