Human USP46/UAF1 protein (Recombinant) (His-Tag) (STJP018652)
SPECIFICATIONS
HostE.coli
ImmunogenHuman
General Information
| Short Description | Recombinant-Human USP46/UAF1-His-Tag protein was developed from e.coli and has a target region of His-Tag. For use in research applications. |
| Applications | SDS-PAGE |
| Host | E.coli |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Concentration | 0.25 mg/mL |
| Formulation | Liquid in 20mM Tris-HCl buffer (pH 8.0) containing 0.15M NaCl, 10% Glycerol, 1mM DTT |
| Storage Instruction | For short term storage, keep at +2C to +8C for up to 1 week. For long term storage, aliquot and store at-20C, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | USP46 |
| Gene ID | 64854 |
| Uniprot ID | UBP46_HUMAN |
| Accession Number | NP_073743.2 |
| Immunogen | Human |
| Immunogen Region | 1-366aa |
| Immunogen Sequence |
Additional Info
| Tissue Specificity | Broadly expressed. |
| Function | Deubiquitinating enzyme that plays a role in behavior, possibly by regulating GABA action. May act by mediating the deubiquitination of GAD1/GAD67. Has almost no deubiquitinating activity by itself and requires the interaction with WDR48 to have a high activity. Not involved in deubiquitination of monoubiquitinated FANCD2. |
| Protein Name | Ubiquitin Carboxyl-Terminal Hydrolase 46Deubiquitinating Enzyme 46Ubiquitin Thioesterase 46Ubiquitin-Specific-Processing Protease 46 |
| Database Links | |
| Cellular Localisation | CytoplasmUsp46/Wdr48/Wdr20 Complex Is Predominantly Cytoplasmic |
| Alternative Protein Names | Ubiquitin Carboxyl-Terminal Hydrolase 46 proteinDeubiquitinating Enzyme 46 proteinUbiquitin Thioesterase 46 proteinUbiquitin-Specific-Processing Protease 46 proteinUSP46 protein |
Information sourced from Uniprot.org