Human USP31 protein (Recombinant) (N-His) (STJP010966)

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STJP010966
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Host: E. coli
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description : Recombinant-Human USP31-N-His protein was developed from e. coli and has a target region of N-His. For use in research applications.
Formulation: Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Storage Instruction: Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at-20 to-80°C for twelve months from the date of receipt.
Gene Symbol: USP31
Gene ID: 57478
Uniprot ID: UBP31_HUMAN
Immunogen Region: Thr595-Ser816
Immunogen: Homo sapiens (Human)
Post Translational Modifications Acetylated at Lys-1264. Acetylation decreases activity. Deacetylated by SIRT1.
Function Deubiquitinase that recognizes and hydrolyzes the peptide bond at the C-terminal Gly of ubiquitin. May play a role in the regulation of NF-kappa-B signaling pathway by deubiquitinating TRAF2. (Microbial infection) Plays a positive role in foot-and-mouth disease and classical swine fever viral infection. Mechanistically, associates with internal ribosomal entry site (IRES) element within the 5'-untranslated region of viral genomes to promote translation of the virus-encoded polyprotein.
Protein Name Ubiquitin Carboxyl-Terminal Hydrolase 31
Deubiquitinating Enzyme 31
Ubiquitin Thioesterase 31
Ubiquitin-Specific-Processing Protease 31
Alternative Protein Names Ubiquitin Carboxyl-Terminal Hydrolase 31 protein
Deubiquitinating Enzyme 31 protein
Ubiquitin Thioesterase 31 protein
Ubiquitin-Specific-Processing Protease 31 protein
USP31 protein
KIAA1203 protein

Information sourced from Uniprot.org

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