Human USP1 protein (Recombinant) (N-His) (STJP007577)
SPECIFICATIONS
HostE.coli
ImmunogenHomo sapiens (Human)
General Information
| Short Description | Recombinant-Human USP1-N-His protein was developed from e.coli for the region N-His. For use in research applications. |
| Applications | ELISA/Immunogen/SDS-PAGE/WB |
| Host | E.coli |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Dilution Range | Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details. |
| Formulation | Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol. |
| Storage Instruction | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at-20 to-80°C for twelve months from the date of receipt. |
Target Information
| Gene Symbol | USP1 |
| Gene ID | 7398 |
| Uniprot ID | UBP1_HUMAN |
| Immunogen | Homo sapiens (Human) |
| Immunogen Region | Arg486-Lys599 |
Additional Info
| Function | Negative regulator of DNA damage repair which specifically deubiquitinates monoubiquitinated FANCD2. Also involved in PCNA-mediated translesion synthesis (TLS) by deubiquitinating monoubiquitinated PCNA. Has almost no deubiquitinating activity by itself and requires the interaction with WDR48 to have a high activity. |
| Protein Name | Ubiquitin Carboxyl-Terminal Hydrolase 1Deubiquitinating Enzyme 1HubpUbiquitin Thioesterase 1Ubiquitin-Specific-Processing Protease 1 Cleaved Into - Ubiquitin Carboxyl-Terminal Hydrolase 1 - N-Terminal Fragment |
| Database Links | Reactome: R-HSA-110314Reactome: R-HSA-6783310 |
| Cellular Localisation | Nucleus |
| Alternative Protein Names | Ubiquitin Carboxyl-Terminal Hydrolase 1 proteinDeubiquitinating Enzyme 1 proteinHubp proteinUbiquitin Thioesterase 1 proteinUbiquitin-Specific-Processing Protease 1 Cleaved Into - Ubiquitin Carboxyl-Terminal Hydrolase 1 - N-Terminal Fragment proteinUSP1 protein |
Information sourced from Uniprot.org