Human USP1 protein (Recombinant) (N-His) (STJP007577)

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STJP007577
$443.48 - $1,940.63
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Host: E. coli
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description : Recombinant-Human USP1-N-His protein was developed from e. coli and has a target region of N-His. For use in research applications.
Formulation: Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Storage Instruction: Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at-20 to-80°C for twelve months from the date of receipt.
Gene Symbol: USP1
Gene ID: 7398
Uniprot ID: UBP1_HUMAN
Immunogen Region: Arg486-Lys599
Immunogen: Homo sapiens (Human)
Function Negative regulator of DNA damage repair which specifically deubiquitinates monoubiquitinated FANCD2. Also involved in PCNA-mediated translesion synthesis (TLS) by deubiquitinating monoubiquitinated PCNA. Has almost no deubiquitinating activity by itself and requires the interaction with WDR48 to have a high activity.
Protein Name Ubiquitin Carboxyl-Terminal Hydrolase 1
Deubiquitinating Enzyme 1
Hubp
Ubiquitin Thioesterase 1
Ubiquitin-Specific-Processing Protease 1 Cleaved Into - Ubiquitin Carboxyl-Terminal Hydrolase 1 - N-Terminal Fragment
Database Links Reactome: R-HSA-110314
Reactome: R-HSA-6783310
Cellular Localisation Nucleus
Alternative Protein Names Ubiquitin Carboxyl-Terminal Hydrolase 1 protein
Deubiquitinating Enzyme 1 protein
Hubp protein
Ubiquitin Thioesterase 1 protein
Ubiquitin-Specific-Processing Protease 1 Cleaved Into - Ubiquitin Carboxyl-Terminal Hydrolase 1 - N-Terminal Fragment protein
USP1 protein

Information sourced from Uniprot.org