Tissue Specificity | Ubiquitous. |
Post Translational Modifications | |
Function | Catalyzes cyclization of the linear tetrapyrrole, hydroxymethylbilane, to the macrocyclic uroporphyrinogen III, the branch point for the various sub-pathways leading to the wide diversity of porphyrins. Porphyrins act as cofactors for a multitude of enzymes that perform a variety of processes within the cell such as methionine synthesis (vitamin B12) or oxygen transport (heme). |
Protein Name | Uroporphyrinogen-Iii SynthaseUroiiisUrosHydroxymethylbilane Hydrolyase CyclizingUroporphyrinogen-Iii Cosynthase |
Database Links | Reactome: R-HSA-189451 |
Cellular Localisation | |
Alternative ELISA Names | Uroporphyrinogen-Iii Synthase ELISA kitUroiiis ELISA kitUros ELISA kitHydroxymethylbilane Hydrolyase Cyclizing ELISA kitUroporphyrinogen-Iii Cosynthase ELISA kitUROS ELISA kit |
output | |
Information sourced from Uniprot.org