Function | Acts as a co-chaperone for HSP90. Prevents the stimulation of HSP90AB1 ATPase activity by AHSA1. Positive factor in promoting PGR function in the cell. May be necessary for proper folding of myosin (Potential). Necessary for normal cell proliferation. Necessary for normal myotube formation and myosin accumulation during muscle cell development. May play a role in erythropoiesis in stroma cells in the spleen. |
Protein Name | Protein Unc-45 Homolog AUnc-45aGcunc-45Smooth Muscle Cell-Associated Protein 1Smap-1 |
Cellular Localisation | CytoplasmPerinuclear RegionNucleusPredominant In The Perinuclear RegionLittle Protein In The Nucleus |
Alternative Protein Names | Protein Unc-45 Homolog A proteinUnc-45a proteinGcunc-45 proteinSmooth Muscle Cell-Associated Protein 1 proteinSmap-1 proteinUNC45A proteinSMAP1 protein |
Information sourced from Uniprot.org