Human UCP3 protein (Recombinant) (N-His) (STJP004975)

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STJP004975
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Host: E. coli
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description : Recombinant-Human UCP3-N-His protein was developed from e. coli and has a target region of N-His. For use in research applications.
Formulation: Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Storage Instruction: Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at-20 to-80°C for twelve months from the date of receipt.
Gene Symbol: UCP3
Gene ID: 7352
Uniprot ID: UCP3_HUMAN
Immunogen Region: Met1-Phe312
Immunogen: Homo sapiens (Human)
Function Putative transmembrane transporter that plays a role in mitochondrial metabolism via an as yet unclear mechanism. Originally, this mitochondrial protein was thought to act as a proton transmembrane transporter from the mitochondrial intermembrane space into the matrix, causing proton leaks through the inner mitochondrial membrane, thereby uncoupling mitochondrial membrane potential generation from ATP synthesis. However, this function is controversial and uncoupling may not be the function, or at least not the main function, but rather a consequence of more conventional metabolite transporter activity.
Protein Name Putative Mitochondrial Transporter Ucp3
Solute Carrier Family 25 Member 9
Uncoupling Protein-3
Ucp 3
Database Links Reactome: R-HSA-167826
Cellular Localisation Mitochondrion Inner Membrane
Multi-Pass Membrane Protein
Alternative Protein Names Putative Mitochondrial Transporter Ucp3 protein
Solute Carrier Family 25 Member 9 protein
Uncoupling Protein-3 protein
Ucp 3 protein
UCP3 protein
SLC25A9 protein

Information sourced from Uniprot.org

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