Human Ubc6/UBE2J2 protein (Recombinant) (His-Tag) (STJP017717)
SPECIFICATIONS
HostE.coli
ImmunogenHuman
General Information
| Short Description | Recombinant-Human Ubc6/UBE2J2-His-Tag protein was developed from e.coli and has a target region of His-Tag. For use in research applications. |
| Applications | SDS-PAGE |
| Host | E.coli |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Concentration | 1 mg/mL |
| Formulation | Liquid in 20mM Tris-HCl buffer (pH 8.0) containing 30% Glycerol, 1mM DTT, 200mM NaCl |
| Storage Instruction | For short term storage, keep at +2C to +8C for up to 1 week. For long term storage, aliquot and store at-20C, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | UBE2J2 |
| Gene ID | 118424 |
| Uniprot ID | UB2J2_HUMAN |
| Accession Number | NP_477515 |
| Immunogen | Human |
| Immunogen Region | 1-226aa |
| Immunogen Sequence |
Additional Info
| Post Translational Modifications | Auto-ubiquitinated. |
| Function | Catalyzes the covalent attachment of ubiquitin to other proteins. Seems to function in the selective degradation of misfolded membrane proteins from the endoplasmic reticulum (ERAD). In cooperation with the GATOR2 complex, catalyzes 'Lys-6'-linked ubiquitination of NPRL2. |
| Protein Name | Ubiquitin-Conjugating Enzyme E2 J2E2 Ubiquitin-Conjugating Enzyme J2Non-Canonical Ubiquitin-Conjugating Enzyme 2Ncube-2 |
| Database Links | Reactome: R-HSA-8866654 Q8N2K1-1Reactome: R-HSA-9609523 Q8N2K1-1Reactome: R-HSA-983168 |
| Cellular Localisation | Endoplasmic Reticulum MembraneSingle-Pass Type Iv Membrane Protein |
| Alternative Protein Names | Ubiquitin-Conjugating Enzyme E2 J2 proteinE2 Ubiquitin-Conjugating Enzyme J2 proteinNon-Canonical Ubiquitin-Conjugating Enzyme 2 proteinNcube-2 proteinUBE2J2 proteinNCUBE2 protein |
Information sourced from Uniprot.org