Human UBC3B/UBE2R2 protein (Recombinant) (His-Tag) (STJP018477)

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STJP018477
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Short Description :Recombinant-Human UBC3B/UBE2R2-His-Tag protein was developed from e.coli and has a target region of His-Tag. For use in research applications.
Applications:SDS-PAGE
Host:E.coli
Note:STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Concentration:0.25 mg/mL
Formulation:Liquid in 20mM Tris-HCl buffer (pH 8.0) containing 0.15M NaCl, 20% Glycerol, 1mM DTT
Storage Instruction:For short term storage, keep at +2C to +8C for up to 1 week. For long term storage, aliquot and store at-20C, and avoid repeat freeze-thaw cycles.
Gene Symbol:UBE2R2
Gene ID:54926
Uniprot ID:UB2R2_HUMAN
Accession Number:NP_060281
Immunogen:Human
Immunogen Region:1-238aa
Immunogen Sequence:MAQQQMT SSQKALMLEL KSLQEEPVEG FRITLVDESD LYNWEVAIFG PPNTLYEGGY FKAHIKFPID YPYSPPTFRF LTKMWHPNIY ENGDVCISIL HPPVDDPQSG ELPSERWNPT QNVRTILLSV ISLLNEPNTF SPANVDASVM FRKWRDSKGK DKEYAEIIRK QVSATKAEAE KDGVKVPTTL AEYCIKTKVP SNDNSS
Function E2 ubiquitin-conjugating enzyme that accepts ubiquitin from an E1 ubiquitin-activating protein, and catalyzes its covalent attachment to other proteins by an E3 ubiquitin-protein ligase complex. In vitro catalyzes monoubiquitination and 'Lys-48'-linked polyubiquitination. Works in collaboration with various Cul1-RING and Cul2-RING E3 ligase complexes. May be involved in degradation of katenin.
Protein Name Ubiquitin-Conjugating Enzyme E2 R2
E2 Ubiquitin-Conjugating Enzyme R2
Ubiquitin Carrier Protein R2
Ubiquitin-Conjugating Enzyme E2-Cdc34b
Ubiquitin-Protein Ligase R2
Database Links Reactome: R-HSA-8866652
Reactome: R-HSA-983168
Cellular Localisation
Alternative Protein Names Ubiquitin-Conjugating Enzyme E2 R2 protein
E2 Ubiquitin-Conjugating Enzyme R2 protein
Ubiquitin Carrier Protein R2 protein
Ubiquitin-Conjugating Enzyme E2-Cdc34b protein
Ubiquitin-Protein Ligase R2 protein
UBE2R2 protein
CDC34B protein
UBC3B protein

Information sourced from Uniprot.org