| Host: | E. coli |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description : | Recombinant-Human UBAP1-N-His protein was developed from e. coli and has a target region of N-His. For use in research applications. |
| Formulation: | Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol. |
| Storage Instruction: | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at-20 to-80°C for twelve months from the date of receipt. |
| Gene Symbol: | UBAP1 |
| Gene ID: | 51271 |
| Uniprot ID: | UBAP1_HUMAN |
| Immunogen Region: | Ala381-Ser502 |
| Immunogen: | Homo sapiens (Human) |
| Function | Component of the ESCRT-I complex, a regulator of vesicular trafficking process. Binds to ubiquitinated cargo proteins and is required for the sorting of endocytic ubiquitinated cargos into multivesicular bodies (MVBs). Plays a role in the proteasomal degradation of ubiquitinated cell-surface proteins, such as EGFR and BST2. |
| Protein Name | Ubiquitin-Associated Protein 1Ubap-1Nasopharyngeal Carcinoma-Associated Gene 20 Protein |
| Database Links | Reactome: R-HSA-162588Reactome: R-HSA-174490Reactome: R-HSA-917729Reactome: R-HSA-9610379Reactome: R-HSA-9615710 |
| Cellular Localisation | CytoplasmCytosolEndosomePredominantly CytosolicRecruited To Endosomes As Part Of The Escrt-I Complex |
| Alternative Protein Names | Ubiquitin-Associated Protein 1 proteinUbap-1 proteinNasopharyngeal Carcinoma-Associated Gene 20 Protein proteinUBAP1 proteinNAG20 protein |
Information sourced from Uniprot.org