Human UACA (Uveal Autoantigen With Coiled Coil Domains And Ankyrin Repeats) Sandwich ELISA Kit Ready-To-Use Kit (STJE0019267)

Human UACA (Uveal Autoantigen With Coiled Coil Domains And Ankyrin Repeats) Sandwich ELISA Kit Ready-To-Use Kit (STJE0019267)

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STJE0019267
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Applications: ELISA
Reactivity: Human
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Sensitivity: 0.132ng/mL
Detection Limit: 0.312-20ng/mL
Short Description : This UACA Sandwich ELISA Kit, Ready-To-Use is an in-vitro enzyme-linked immunosorbent assay for the measurement of samples in human tissue homogenates or other biological fluids..
Storage Instruction: The whole kit may be stored at-20°C for up to 12 months from receipt. An unopened kit may be stored in the fridge at 2-8°C for up to 6 months. Once opened store individual kit contents according to components table provided with the kit.
Assay Time: 3 hrs
Gene Symbol: UACA
Gene ID: 55075
Uniprot ID: UACA_HUMAN
Immunogen Region: Ready-To-Use
Sample Type: tissue homogenates or other biological fluids.
Tissue Specificity Highly expressed in skeletal muscle, heart, kidney and pancreas. Expressed in choroid, retina and epidermal melanocytes. Expressed in eye muscles and thyroid follicular cells.
Post Translational Modifications
Function Regulates APAF1 expression and plays an important role in the regulation of stress-induced apoptosis. Promotes apoptosis by regulating three pathways, apoptosome up-regulation, LGALS3/galectin-3 down-regulation and NF-kappa-B inactivation. Regulates the redistribution of APAF1 into the nucleus after proapoptotic stress. Down-regulates the expression of LGALS3 by inhibiting NFKB1. Modulates isoactin dynamics to regulate the morphological alterations required for cell growth and motility. Interaction with ARF6 may modulate cell shape and motility after injury. May be involved in multiple neurite formation.
Protein Name Uveal Autoantigen With Coiled-Coil Domains And Ankyrin Repeats
Database Links Reactome: R-HSA-9013407
Reactome: R-HSA-9627069
Cellular Localisation Nucleus
Cytoplasm
Cytoskeleton
Expressed Diffusely In Cytoplasm
Alternative ELISA Names Uveal Autoantigen With Coiled-Coil Domains And Ankyrin Repeats ELISA kit
UACA ELISA kit
KIAA1561 ELISA kit
output

Information sourced from Uniprot.org

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