Human UACA protein (Recombinant) (N-His) (STJP005959)

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STJP005959
€410.63 - €1,796.88
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Host: E. coli
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description : Recombinant-Human UACA-N-His protein was developed from e. coli and has a target region of N-His. For use in research applications.
Formulation: Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Storage Instruction: Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at-20 to-80°C for twelve months from the date of receipt.
Gene Symbol: UACA
Gene ID: 55075
Uniprot ID: UACA_HUMAN
Immunogen Region: Ala29-Glu209
Immunogen: Homo sapiens (Human)
Function Regulates APAF1 expression and plays an important role in the regulation of stress-induced apoptosis. Promotes apoptosis by regulating three pathways, apoptosome up-regulation, LGALS3/galectin-3 down-regulation and NF-kappa-B inactivation. Regulates the redistribution of APAF1 into the nucleus after proapoptotic stress. Down-regulates the expression of LGALS3 by inhibiting NFKB1. Modulates isoactin dynamics to regulate the morphological alterations required for cell growth and motility. Interaction with ARF6 may modulate cell shape and motility after injury. May be involved in multiple neurite formation.
Protein Name Uveal Autoantigen With Coiled-Coil Domains And Ankyrin Repeats
Database Links Reactome: R-HSA-9013407
Reactome: R-HSA-9627069
Cellular Localisation Nucleus
Cytoplasm
Cytoskeleton
Expressed Diffusely In Cytoplasm
Alternative Protein Names Uveal Autoantigen With Coiled-Coil Domains And Ankyrin Repeats protein
UACA protein
KIAA1561 protein

Information sourced from Uniprot.org

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