Human UACA protein (Recombinant) (N-His) (STJP005959)
SPECIFICATIONS
HostE.coli
ImmunogenHomo sapiens (Human)
General Information
| Short Description | Recombinant-Human UACA-N-His protein was developed from e.coli for the region N-His. For use in research applications. |
| Applications | ELISA/Immunogen/SDS-PAGE/WB |
| Host | E.coli |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Dilution Range | Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details. |
| Formulation | Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol. |
| Storage Instruction | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at-20 to-80°C for twelve months from the date of receipt. |
Target Information
| Gene Symbol | UACA |
| Gene ID | 55075 |
| Uniprot ID | UACA_HUMAN |
| Immunogen | Homo sapiens (Human) |
| Immunogen Region | Ala29-Glu209 |
Additional Info
| Function | Regulates APAF1 expression and plays an important role in the regulation of stress-induced apoptosis. Promotes apoptosis by regulating three pathways, apoptosome up-regulation, LGALS3/galectin-3 down-regulation and NF-kappa-B inactivation. Regulates the redistribution of APAF1 into the nucleus after proapoptotic stress. Down-regulates the expression of LGALS3 by inhibiting NFKB1. Modulates isoactin dynamics to regulate the morphological alterations required for cell growth and motility. Interaction with ARF6 may modulate cell shape and motility after injury. May be involved in multiple neurite formation. |
| Protein Name | Uveal Autoantigen With Coiled-Coil Domains And Ankyrin Repeats |
| Database Links | Reactome: R-HSA-9013407Reactome: R-HSA-9627069 |
| Cellular Localisation | NucleusCytoplasmCytoskeletonExpressed Diffusely In Cytoplasm |
| Alternative Protein Names | Uveal Autoantigen With Coiled-Coil Domains And Ankyrin Repeats proteinUACA proteinKIAA1561 protein |
Information sourced from Uniprot.org