Tissue Specificity | |
Post Translational Modifications | |
Function | May be involved in dorsoventral axis formation. Seems to antagonize BMP signaling by forming ternary complexes with CHRD and BMPs, thereby preventing BMPs from binding to their receptors. In addition to the anti-BMP function, also has pro-BMP activity, partly mediated by cleavage and degradation of CHRD, which releases BMPs from ternary complexes. May be an important modulator of BMP-regulated cartilage development and chondrocyte differentiation. May play a role in thymocyte development. |
Protein Name | Twisted Gastrulation Protein Homolog 1 |
Database Links | |
Cellular Localisation | Secreted |
Alternative ELISA Names | Twisted Gastrulation Protein Homolog 1 ELISA kitTWSG1 ELISA kitTSG ELISA kitPSEC0250 ELISA kit |
output | |
Information sourced from Uniprot.org