Human TWF1 protein (Recombinant) (N-His) (STJP005251)

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STJP005251
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Host: E. coli
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description : Recombinant-Human TWF1-N-His protein was developed from e. coli and has a target region of N-His. For use in research applications.
Formulation: Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Storage Instruction: Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at-20 to-80°C for twelve months from the date of receipt.
Gene Symbol: TWF1
Gene ID: 5756
Uniprot ID: TWF1_HUMAN
Immunogen Region: Met1-Ser252
Immunogen: Homo sapiens (Human)
Post Translational Modifications Phosphorylated on serine and threonine residues.
Function Actin-binding protein involved in motile and morphological processes. Inhibits actin polymerization, likely by sequestering G-actin. By capping the barbed ends of filaments, it also regulates motility. Seems to play an important role in clathrin-mediated endocytosis and distribution of endocytic organelles.
Protein Name Twinfilin-1
Protein A6
Protein Tyrosine Kinase 9
Database Links Reactome: R-HSA-9013418
Reactome: R-HSA-9662360
Reactome: R-HSA-9662361
Cellular Localisation Cytoplasm
Cytoskeleton
Diffuse Cytoplasmic Localization With Perinuclear And G-Actin-Rich Cortical Actin Structures Sublocalization
Also Found At Membrane Ruffles And Cell-Cell Contacts
Alternative Protein Names Twinfilin-1 protein
Protein A6 protein
Protein Tyrosine Kinase 9 protein
TWF1 protein
PTK9 protein

Information sourced from Uniprot.org