Post Translational Modifications | Phosphorylated on serine and threonine residues. |
Function | Actin-binding protein involved in motile and morphological processes. Inhibits actin polymerization, likely by sequestering G-actin. By capping the barbed ends of filaments, it also regulates motility. Seems to play an important role in clathrin-mediated endocytosis and distribution of endocytic organelles. |
Protein Name | Twinfilin-1Protein A6Protein Tyrosine Kinase 9 |
Database Links | Reactome: R-HSA-9013418Reactome: R-HSA-9662360Reactome: R-HSA-9662361 |
Cellular Localisation | CytoplasmCytoskeletonDiffuse Cytoplasmic Localization With Perinuclear And G-Actin-Rich Cortical Actin Structures SublocalizationAlso Found At Membrane Ruffles And Cell-Cell Contacts |
Alternative Protein Names | Twinfilin-1 proteinProtein A6 proteinProtein Tyrosine Kinase 9 proteinTWF1 proteinPTK9 protein |
Information sourced from Uniprot.org