Human TSPO protein (Recombinant) (N-His) (STJP011688)

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STJP011688
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Host: E. coli
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description : Recombinant-Human TSPO-N-His protein was developed from e. coli and has a target region of N-His. For use in research applications.
Formulation: Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Storage Instruction: Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for one week. Store at-20 to-80°C for twelve months from the date of receipt.
Gene Symbol: TSPO
Gene ID: 706
Uniprot ID: TSPO_HUMAN
Immunogen Region: Ala2-Leu82
Immunogen: Homo sapiens (Human)
Function Can bind protoporphyrin IX and may play a role in the transport of porphyrins and heme. Promotes the transport of cholesterol across mitochondrial membranes and may play a role in lipid metabolism, but its precise physiological role is controversial. It is apparently not required for steroid hormone biosynthesis. Was initially identified as peripheral-type benzodiazepine receptor.can also bind isoquinoline carboxamides.
Protein Name Translocator Protein
Mitochondrial Benzodiazepine Receptor
Pkbs
Peripheral-Type Benzodiazepine Receptor
Pbr
Database Links Reactome: R-HSA-196108
Cellular Localisation Mitochondrion Membrane
Multi-Pass Membrane Protein
Alternative Protein Names Translocator Protein protein
Mitochondrial Benzodiazepine Receptor protein
Pkbs protein
Peripheral-Type Benzodiazepine Receptor protein
Pbr protein
TSPO protein
BZRP protein
MBR protein

Information sourced from Uniprot.org