Human TSLPR protein (Recombinant) (C-hFc) (STJP020258)

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STJP020258-100
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Covered by St John's Laboratory Guarantee

Host: HEK293 cells
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Conjugation: Unconjugated
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Determination Method: < 1 EU/Mu g of the protein by LAL method.
Gene Symbol: CRLF2
Gene ID: 64109
Uniprot ID: CRLF2_HUMAN
Immunogen Region: Gly25-Lys231
Immunogen: Recombinant Human TSLPR Protein is expressed from Expi293 with hFc tag at the C-terminal.；It contains Gly25-Lys231.
Immunogen Sequence: GAAEGVQIQIIYFNLETVQV TWNASKYSRTNLTFHYRFNG DEAYDQCTNYLLQEGHTSGC LLDAEQRDDILYFSIRNGTH PVFTASRWMVYYLKPSSPKH VRFSWHQDAVTVTCSDLSYG DLLYEVQYRSPFDTEWQSKQ ENTCNVTIEGLDAEKCYSFW VRVKAMEDVYGPDTYPSDWS EVTCWQRGEIRDACAETPTP PKPKLSK
Tissue Specificity Expressed in heart, skeletal muscle, kidney and adult and fetal liver. Primarily expressed in dendrites and monocytes. Weakly expressed in T-cells.
Function Receptor for thymic stromal lymphopoietin (TSLP). Forms a functional complex with TSLP and IL7R which is capable of stimulating cell proliferation through activation of STAT3 and STAT5. Also activates JAK2. Implicated in the development of the hematopoietic system.
Protein Name Cytokine Receptor-Like Factor 2
Cytokine Receptor-Like 2
Il-Xr
Thymic Stromal Lymphopoietin Protein Receptor
Tslp Receptor
Database Links Reactome: R-HSA-1266695
Cellular Localisation Isoform 1: Cell Membrane
Single-Pass Type I Membrane Protein
Isoform 2: Secreted
Alternative Protein Names Cytokine Receptor-Like Factor 2 protein
Cytokine Receptor-Like 2 protein
Il-Xr protein
Thymic Stromal Lymphopoietin Protein Receptor protein
Tslp Receptor protein
CRLF2 protein
CRL2 protein
ILXR protein
TSLPR protein

Information sourced from Uniprot.org

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