Human TSLPR/CRLF2 protein (Recombinant) (C-Strep) (STJP009517)

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STJP009517
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Host: Mammalian Cells
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description : Recombinant-Human TSLPR/CRLF2-C-Strep protein was developed from mammalian cells and has a target region of C-Strep. For use in research applications.
Formulation: Lyophilized from a solution in PBS pH 7.4, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Storage Instruction: Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at-20 to-80°C for twelve months from the date of receipt.
Gene Symbol: CRLF2
Gene ID: 64109
Uniprot ID: CRLF2_HUMAN
Immunogen Region: Gln23-Lys231
Immunogen: Homo sapiens (Human)
Function Receptor for thymic stromal lymphopoietin (TSLP). Forms a functional complex with TSLP and IL7R which is capable of stimulating cell proliferation through activation of STAT3 and STAT5. Also activates JAK2. Implicated in the development of the hematopoietic system.
Protein Name Cytokine Receptor-Like Factor 2
Cytokine Receptor-Like 2
Il-Xr
Thymic Stromal Lymphopoietin Protein Receptor
Tslp Receptor
Database Links Reactome: R-HSA-1266695
Cellular Localisation Isoform 1: Cell Membrane
Single-Pass Type I Membrane Protein
Isoform 2: Secreted
Alternative Protein Names Cytokine Receptor-Like Factor 2 protein
Cytokine Receptor-Like 2 protein
Il-Xr protein
Thymic Stromal Lymphopoietin Protein Receptor protein
Tslp Receptor protein
CRLF2 protein
CRL2 protein
ILXR protein
TSLPR protein

Information sourced from Uniprot.org

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