| Host: | Mammalian Cells |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description : | Recombinant-Active-Human TSLPR/CRLF2-C-hFc-His protein was developed from mammalian cells and has a target region of C-hFc-His. For use in research applications. |
| Formulation: | Lyophilized from a solution in PBS pH 7.4, 5% Trehalose, 5% Mannitol. |
| Dilution Range: | Reconstitute in sterile water for a stock solution. |
| Storage Instruction: | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for one week. Store at-20 to-80°C for twelve months from the date of receipt. |
| Endotoxin: | <0.1 EU/Mu g of the protein by the LAL method. |
| Gene Symbol: | CRLF2 |
| Gene ID: | 64109 |
| Uniprot ID: | CRLF2_HUMAN |
| Immunogen Region: | Gly25-Lys231 |
| Immunogen: | Homo sapiens (Human) |
| Function | Receptor for thymic stromal lymphopoietin (TSLP). Forms a functional complex with TSLP and IL7R which is capable of stimulating cell proliferation through activation of STAT3 and STAT5. Also activates JAK2. Implicated in the development of the hematopoietic system. |
| Protein Name | Cytokine Receptor-Like Factor 2Cytokine Receptor-Like 2Il-XrThymic Stromal Lymphopoietin Protein ReceptorTslp Receptor |
| Database Links | Reactome: R-HSA-1266695 |
| Cellular Localisation | Isoform 1: Cell MembraneSingle-Pass Type I Membrane ProteinIsoform 2: Secreted |
| Alternative Protein Names | Cytokine Receptor-Like Factor 2 proteinCytokine Receptor-Like 2 proteinIl-Xr proteinThymic Stromal Lymphopoietin Protein Receptor proteinTslp Receptor proteinCRLF2 proteinCRL2 proteinILXR proteinTSLPR protein |
Information sourced from Uniprot.org
